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Subject3 new papers in your 05-10-2026 Prodromos digest
Prodromos
3 new relevant papers for you — 05-10-2026
  • 1. Oral step-down versus continued intravenous therapy for Gram-negative bacteraemia Randomised Controlled Trial
    Infectious diseases journal · this week
    Picked because: Tests early oral switch in uncomplicated bacteraemia, a decision made on every ward round.
    Findings: Early oral step-down was non-inferior to continued intravenous therapy for 90-day mortality, with shorter hospital stays.
    👍 Relevant👎 Not relevant⭐ Save
  • 2. Procalcitonin-guided antibiotic discontinuation in sepsis Systematic Review/Meta-analysis
    Infectious diseases journal · this week
    Picked because: Pooled evidence on a widely used stopping rule; directly informs local sepsis pathways.
    Findings: Procalcitonin-guided stopping shortened antibiotic courses by about two days, with no increase in mortality.
    👍 Relevant👎 Not relevant⭐ Save
  • 3. Long-acting injectable PrEP uptake in sexual health clinics Preprint · not peer-reviewed
    Preprint server · this week
    Picked because: Early real-world uptake data relevant to service planning.

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